Cardiothoracic & vascular anesthesia
Development and Validation of a Prediction Score for Low-Cardiac-Output Syndrome After Adult Cardiac Surgery
Authors' conclusion
The authors developed a clinical score to facilitate the prediction of low- cardiac-output syndrome after adult cardiac surgery.
Study context
- Population
- Adults undergoing on-pump cardiac surgery, April 2016 to March 2021retained for final analyses
- Participants
- 2,806 adults
- Outcome
- Low-cardiac-output syndrome after adult cardiac surgery
Methodological detailsprediction score development and validation, single-centre, tertiary hospital, stepwise backward multivariate logistic regression, bootstrap validation
- Prediction score development and validation
- Single-centre
- Tertiary hospital
- Stepwise backward multivariate logistic regression
- Bootstrap validation
Main finding
As reported in the abstract
Prediction of low-cardiac-output syndrome
| Group | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| Score | 68% | 79% | 33% | 94% |
Score
Sensitivity68%
Specificity79%
PPV33%
NPV94%
- Model AUC (good discriminative ability)
- 0.8 (95% CI: 077-0.84)
Observational data: associations, not effects.
Original publication
Development and Validation of a Prediction Score for Low-Cardiac-Output Syndrome After Adult Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 19 June 2023. doi:10.
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