Anaesthetic drugs & techniques

Development and temporal validation of a simple computed tomography-based (CT-based) body surface landmark approach for optimising central venous catheter tip position in the superior vena cava

Eur J AnaesthesiolPublished Single-centre prospective observational cohort study

Main finding · Proportion of appropriately placed catheter tipsResult — go to the resultAdjusted odds ratio for appropriate positioning 4.68 95% CI 1.97–12.27

Authors' conclusion

A CT-based body surface landmark approach was associated with improved consistency of appropriate CVC tip placement and enables patient-specific estimation of insertion depth.

Study context

Population
Adult patients undergoing surgery requiring central venous catheter (CVC) placement via the right internal jugular vein with preoperative chest CT; tertiary care hospital in Japan, February 2017 to June 2019included after exclusions, per cohort · derivation cohort 86 · validation cohort 100
Participants
100 vs 86
Exposure
Validation cohort vs derivation cohort
  • Validation cohortn = 100
  • Derivation cohortn = 86
Outcome
Proportion of appropriately placed catheter tips
Methodological detailsdevelopment and temporal validation
  • Development and temporal validation

Main finding

As reported in the abstract

Adjusted odds ratio for appropriate positioning

4.68

95% CI 1.97–12.27

By group

Model-guided placement
adjusted odds ratio for appropriate positioning 4.68 (95% CI 1.97–12.27)

Observational data: associations, not effects.

Further findings

Final model for optimal insertion depth (OID)

Sole predictor: insertion point-to-body surface landmark distance (ILD), landmark corresponding to the CT-identified midpoint of Zone B
OID (cm) = 0.64 × ILD + 3.64

Model performance

Moderate explanatory ability (R2) in both cohorts
≈50%
Good calibration in both cohorts

Original publication

Development and temporal validation of a simple CT-based body surface landmark approach for optimising central venous catheter tip position in the superior vena cava. Eur J Anaesthesiol. Published 20 October 2026. doi:10.1097/eja.0000000000002490

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