Cardiothoracic & vascular anesthesia
Discharge to Nonhome Locations and Association With Long-term Survival After Cardiac Surgery in Australia and New Zealand Intensive Care Units: A Retrospective Multicenter Cohort Study
Main finding · Survival (Cox proportional hazards)Result — go to the resultHR for death 1.91 95% CI 1.75–2.09Authors' conclusion
NHD after cardiac surgery is associated independently with decreased long-term survival, with the highest risk observed within the first year.
Study context
- Population
- Adults (≥16 years) who underwent valvular surgery, CABG, or both and survived hospital discharge; 74 intensive care units (ICUs) in Australia and New Zealand, 2018–2023
- Participants
- 92,865 adults · 74 ICUs
- Exposure
- Nonhome discharge vs home discharge
- Nonhome discharge (NHD)n = 13,444
- Outcome
- Survival (Cox proportional hazards)
- Follow-up
- Up to 4 years
Methodological detailsmulticentre, registry-based
- Multicentre
- Registry-based
Main finding
As reported in the abstract
HR for death
1.91
95% CI 1.75–2.09
NHD vs HD
HR for death 1.91 (95% CI 1.75–2.09)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | P value | |
|---|---|---|---|
| Survival by age (subgroup)NHD vs HD | HR for death, age <65 years 2.58 (95% CI 2.20–3.03) | ||
| Survival by age (subgroup)NHD vs HD | HR for death, age ≥65 years 1.71 (95% CI 1.54–1.89) | P for interaction < 0.001 | |
| 0.20.5125Ratio (log scale) |
- Survival by age (subgroup): interaction P: pinteraction < 0.001
Survival by NHD location
- No significant differences between NHD locations
Survival by surgery type and emergency status (subgroup)
- Lower survival after NHD vs home discharge (HD) across all surgery types, emergency and elective
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Discharge to Nonhome Locations and Association With Long-term Survival After Cardiac Surgery in Australia and New Zealand Intensive Care Units: A Retrospective Multicenter Cohort Study. J Cardiothorac Vasc Anesth. Published 11 June 2025. doi:10. 1053/ j. jvca. 2025. 06. 017
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