Hemodynamics, fluids & transfusion
Effect of volume infusion on left atrial strain in acute circulatory failure
Authors' conclusion
LAS is severely altered during acute circulatory failure. LAS components significantly increase during fluid administration, but cannot be used to predict or assess fluid responsiveness.
Study context
- Population
- ICU patients with acute circulatory failure receiving volume expansion (rapid infusion of 500 mL crystalloid), French ICUincluded in final analysis
- Participants
- 38 patients
- Exposure
- Left atrial strain before vs after volume expansion; fluid responders vs non-responders
- Outcome
- LAS and its variation during volume expansion; relationship between LAS components and fluid responsiveness (increase in LV outflow tract VTI ≥ 10%)
Methodological detailssingle-centre, Transthoracic echocardiography before and after fluid infusion; Left atrial strain (LAS) analysis offline
- Single-centre
- Transthoracic echocardiography before and after fluid infusion; LAS analysis offline
Main finding
As reported in the abstract
Baseline LAS (median [IQR])
LAS reservoir (LASr), %
19
15–32
LAS conduit (LAScd), %
−9
−19 - −7
LAS contraction (LASct), %
- 9
−13 - −5
Observational data: associations, not effects.
Further findings
Fluid responders
- Fluid responders
- 17 (45%)
LAS analysis feasibility and reproducibility
- Good feasibility and reproducibility
Original publication
Effect of volume infusion on left atrial strain in acute circulatory failure. Ann Intensive Care. Published 9 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →