Hemodynamics, fluids & transfusion
Evaluating the Utility of Portal Vein Pulsatility Index for Detecting Fluid Unresponsiveness in the Intensive Care Unit
Authors' conclusion
Although PVP has limited value as the sole indicator for fluid management decisions, it can be used as a stopping rule or combined with other diagnostic tests to improve the accuracy of fluid responsiveness assessment.
Study context
- Population
- ICU patients evaluated by ultrasonography of portal vein flow before fluid expansion; non-responders = <15% increase in left ventricle outflow tract velocity-time integral after 500 mL Ringer LactateJanuary–October 2022
- Participants
- 63 patients
- Outcome
- Capacity of PVP to detect fluid unresponsiveness
Methodological detailsretrospective, single-centre, Tertiary medical-surgical ICU, Buenos Aires, Argentina
- Retrospective
- Single-centre
- Tertiary medical-surgical ICU, Buenos Aires, Argentina
Performance
As reported in the abstract
Fluid unresponsiveness
| Test or model | AUC (95% CI) | Threshold | Sensitivity (95% CI) | Specificity (95% CI) | PPV | NPV (95% CI) |
|---|---|---|---|---|---|---|
| PVP | 0.708 (0.580 to 0.816) | >32% | 30.8% (17% to 47.6%) | 100% (85.8 to 100) | 100% | 47.1% (41.9% to 52.3%) |
PVP
AUC (95% CI)0.708 (0.580 to 0.816)
Threshold>32%
Sensitivity (95% CI)30.8% (17% to 47.6%)
Specificity (95% CI)100% (85.8 to 100)
PPV100%
NPV (95% CI)47.1% (41.9% to 52.3%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Evaluating the Utility of Portal Vein Pulsatility Index for Detecting Fluid Unresponsiveness in the Intensive Care Unit. J Cardiothorac Vasc Anesth. Published 25 May 2023. doi:10.
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