Cardiothoracic & vascular anesthesia
Effect of preoperative thoracic paravertebral block using liposomal bupivacaine combined with drainage-tube patient-controlled analgesia on postoperative pain after thoracoscopic lobectomy: a prospective, multicentre, double-blind, randomized controlled study protocol
Study context
- Population
- Patients undergoing thoracoscopic lobectomytarget sample size
- Participants
- 228 patients
- Planned comparison
- Liposomal bupivacaine (LB) vs standard bupivacaine (SB) thoracic paravertebral block (TPVB), each with or without drainage-tube patient-controlled analgesia (PCA)
- SBn = 57reference
- SB + DTAn = 57
- LBn = 57
- LB + DTAn = 57
- Primary endpoint
- Mean Numerical Rating Scale (NRS) pain score at rest
- Follow-up
- 72 h
Methodological detailsprospective, multicentre, double-blind
- Prospective
- Multicentre
- Double-blind
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Effect of preoperative thoracic paravertebral block using liposomal bupivacaine combined with drainage-tube patient-controlled analgesia on postoperative pain after thoracoscopic lobectomy: a prospective, multicentre, double-blind, randomized controlled study protocol. Perioper Med (Lond). Published 6 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →