Cardiothoracic & vascular anesthesia

Effects of Postoperative Blood Pressure Management on Delirium Among Patients in the Intensive Care Unit After Cardiac Surgery: An Observational Cohort Study

J Cardiothorac Vasc AnesthPublished Observational cohort study

Authors' conclusion

The MAP range bands above and below the authors' reference band of 60-to- 69 mmHg were associated with decreased risk of ICU delirium development; however, this was difficult to reconcile with a plausible biologic mechanism. Therefore, the authors did not find a correlation between early postoperative MAP control and increased risk of the development of ICU delirium after cardiac surgery.

Study context

Population
Cardiac surgery patients admitted to the cardiovascular intensive care unit (ICU) after surgery
Participants
517 patients
Exposure
Time spent in mean arterial pressure (MAP) range bands vs reference band 60-to-69 mmHg
Outcome
Delirium
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Per 10 minutes
Each group vs 60-to-69 mmHgAdjusted hazard ratio (95% CI)
50-to-59 mmHg
0.907(0.861–0.955)
70-to-79 mmHg
0.923(0.902–0.944)
90-to-99 mmHg
0.898(0.853–0.945)

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Effects of Postoperative Blood Pressure Management on Delirium Among Patients in the Intensive Care Unit After Cardiac Surgery: An Observational Cohort Study. J Cardiothorac Vasc Anesth. Published 10 May 2023. doi:10.1053/j.jvca.2023.05.011

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