Cardiothoracic & vascular anesthesia
Effects of Postoperative Blood Pressure Management on Delirium Among Patients in the Intensive Care Unit After Cardiac Surgery: An Observational Cohort Study
Authors' conclusion
The MAP range bands above and below the authors' reference band of 60-to- 69 mmHg were associated with decreased risk of ICU delirium development; however, this was difficult to reconcile with a plausible biologic mechanism. Therefore, the authors did not find a correlation between early postoperative MAP control and increased risk of the development of ICU delirium after cardiac surgery.
Study context
- Population
- Cardiac surgery patients admitted to the cardiovascular intensive care unit (ICU) after surgery
- Participants
- 517 patients
- Exposure
- Time spent in mean arterial pressure (MAP) range bands vs reference band 60-to-69 mmHg
- Outcome
- Delirium
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Each group vs 60-to-69 mmHgAdjusted hazard ratio (95% CI)
50-to-59 mmHg
0.907(0.861–0.955)
70-to-79 mmHg
0.923(0.902–0.944)
90-to-99 mmHg
0.898(0.853–0.945)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effects of Postoperative Blood Pressure Management on Delirium Among Patients in the Intensive Care Unit After Cardiac Surgery: An Observational Cohort Study. J Cardiothorac Vasc Anesth. Published 10 May 2023. doi:10. 1053/ j. jvca. 2023. 05. 011
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