Cardiothoracic & vascular anesthesia

Efficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis

Br J AnaesthPublished Systematic review and meta-analysis of randomised trials and prospective observational trials

Pooled result · Hospital LOSResult — go to the resultMean difference −1.40 days 95% CI −2.19 to −0.61

Authors' conclusion

In cardiac surgery, ERP can reduce LOS in the ICU and hospital and ventilatory time.

Study context

Population
Patients undergoing cardiac surgery
Participants
2,625 patients · 18 studies
Comparison
ERP or fast-track (FT) programmes vs control in cardiac surgery
Outcome
Hospital LOS
Methodological detailsrandom-effects model, PRISMA
  • Random-effects model
  • PRISMA

Pooled result

As reported in the abstract

Mean difference

−1.40 days

95% CI −2.19 to −0.61

P = 0.001

ERP or FT vs Control
mean difference −1.40 days (95% CI −2.19 to −0.61); P = 0.001

Further pooled results

OutcomeMean difference (h) (95% CI)P value
ICU LOS−13.22 (−21.75 to −4.68)P = 0.006
Ventilation time−4.68 (−7.85 to −1.52)P = 0.008
OutcomeMean difference (days) (95% CI)
Hospital LOS, ERP vs FT (subgroup)FT vs Control−0.30 (−0.88 to 0.27)
OutcomeMean difference (days) (95% CI)
Hospital LOS, ERP vs FT (subgroup)ERP vs Control2.11 (−3.52 to 0.71)
Hospital length of stay (LOS), ERP vs FT (subgroup) — ERP demonstrated an additive value above FT for hospital LOS
P=0.003

Original publication

Efficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis. Br J Anaesth. Published 25 April 2025. doi:10.1016/j.bja.2025.03.019

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