Cardiothoracic & vascular anesthesia

From fast track to enhanced recovery after Cardiac surgery: 15 years of experience with the Leipzig concept in a specialized post-anesthesia care unit

J Clin AnesthPublished Retrospective cohort study

Authors' conclusion

This study presents the largest collection of consecutive ERACS patients ever collected and demonstrates the safety and efficacy of ERACS management with a specialized PACU, highlighting the benefits of continuous protocol optimization.

Study context

Population
Patients admitted to a specialized postanaesthesia care unit (PACU) after cardiac surgery and managed per Enhanced Recovery After Cardiac Surgery (ERACS) protocol, Heart Center Leipzig, November 2005–December 202020,773 analysed
Participants
23,724 patients
Outcome
ERACS utilization in PACU after cardiac surgery and in-hospital mortality over time
Follow-up
2006 to 2020
Methodological detailssingle-centre, multivariable-adjusted
  • Single-centre
  • Multivariable-adjusted

Main finding

As reported in the abstract

ERACS PACU utilization in 2006

19%

ERACS PACU utilization in 2020

60%

Observational data: associations, not effects.

Further findings

OutcomeP value
In-hospital mortality, sufentanil vs remifentanilSignificantly lower with sufentanilP = 0.005

In-hospital mortality (subgroups)

Higher with EuroSCORE II ≥6%
P < 0.001
Higher with complex procedures
P = 0.04
Higher with age ≥ 75 years
P < 0.001

Original publication

From fast track to enhanced recovery after Cardiac surgery: 15 years of experience with the Leipzig concept in a specialized post-anesthesia care unit. J Clin Anesth. Published 4 February 2026. doi:10.1016/j.jclinane.2026.112137

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