Cardiothoracic & vascular anesthesia
Evaluation of Frailty Measures and Short-term Outcomes After Lung Transplantation
Authors' conclusion
Both phenotypic and cumulative deficit models measured before transplantation are associated with short-term outcomes after lung transplantation.
Study context
- Population
- Lung transplant recipients with frailty assessments before transplantation
- Participants
- 515 recipients
- Exposure
- Frailty measures before transplantation and short-term outcomes
- Outcome
- 1-year survival and hospital-free days (HFDs) in the first 90 days after transplantation
Methodological detailsmultivariate adjusted
- Multivariate adjusted
Main finding
As reported in the abstract
Frail by frailty index (FI) (FI ≥ 0.25) before transplantation
51.3%
Frail by short physical performance battery (SPPB) before transplantation
0
Greater frailty by FI associated with fewer hospital-free days (HFDs) among discharged patients
−0.006
per 0.01 unit worsening; 95% CI, −0.01 to −0.002
Greater SPPB deficits associated with decreased odds of 1-year survival
0.51
OR per 1 unit worsening; 95% CI, 0.28–0.93
Observational data: associations, not effects.
Further findings
Correlation among frailty measurements
- Overall poor
Original publication
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