Respiratory failure & ventilation
Extracorporeal Membrane Oxygenation Without Invasive Ventilation for Respiratory Failure in Adults: A Systematic Review*
Authors' conclusion
Awake ECMO is feasible in selected patients, although the effect on outcome remains to be demonstrated. Mortality is almost 60% in patients who failed awake ECMO strategy.
Study context
- Population
- Adults with respiratory failure receiving awake extracorporeal membrane oxygenation (ECMO) without invasive ventilation
- Participants
- 467 adults · 57 studies
- Outcome
- Awake ECMO failure (need for intubation)
Methodological detailspooled estimates, subgroup analyses by setting, PubMed, Web of Science and Scopus searched, 28 of 57 studies were case reports
- Pooled estimates
- Subgroup analyses by setting
- PubMed, Web of Science and Scopus searched
- 28 of 57 studies were case reports
Pooled result
As reported in the abstract
Awake ECMO failure (subgroup)
Further pooled results
Mortality at longest follow-up, all awake ECMO patients
- Deaths at longest follow-up
- 121 of 439
- Pooled estimate of mortality
- 28% (95% CI 22.3-33.6%)
Mortality in patients who failed awake ECMO strategy (subgroup)
- Deaths in patients who failed awake ECMO
- 43 of 74
- Pooled estimate of mortality
- 57.2% (95% CI 40.2-74.3%)
Safety
- Cases of cannula self-removal
- 2
Original publication
Extracorporeal Membrane Oxygenation Without Invasive Ventilation for Respiratory Failure in Adults: A Systematic Review*. Crit Care Med. Published 28 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →