Cardiothoracic & vascular anesthesia
Extrapleural infusion of levobupivacaine versus levobupivacaine‐sufentanil‐adrenaline after video‐assisted thoracoscopic surgery (video-assisted thoracic surgery (VATS)): A randomised controlled trial
Authors' conclusion
For a continuous extrapleural block, and compared to plain levobupivacaine at 13.5 mg h-1 , levobupivacaine at 6.25 mg h-1 with addition of sufentanil and adrenaline did not decrease postoperative morphine consumption.
Study context
- Population
- Patients undergoing video-assisted thoracoscopic surgery (VATS)
- Participants
- 60 patients
- Comparison
- LBSA vs LB
- Primary endpoint
- Cumulative morphine dose administered as PCA (PCA-morphine)
- Follow-up
- 48 and 72 h
Primary result
As reported in the abstract
Cumulative PCA-morphine dose · 48 h
P = 0.378
Secondary outcomes
Cumulative PCA-morphine dose · 72 h
P = 0.738
Pain numerical rating scale (NRS) at rest and after two deep breaths
- Median NRS 3 or lower at all time points in both groups
Peak expiratory flow (PEF)
- PEF did not differ between groups
QoR-15 score · 3 weeks postoperatively
- Only the LB group returned to baseline QoR-15 score
Serum levobupivacaine concentrations · 48 and 72 h
- Higher in the LB group, but well below toxic
Safety
Nausea, dizziness, pruritus and headache
- Incidence equally low overall
Original publication
Extrapleural infusion of levobupivacaine versus levobupivacaine‐sufentanil‐adrenaline after video‐assisted thoracoscopic surgery (VATS): A randomised controlled trial. Acta Anaesthesiol Scand. Published 21 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →