Cardiothoracic & vascular anesthesia

Feasibility of estimating cardiac indices using cardiac surgery anesthesia records in a multicenter cohort

J Clin Monit ComputPublished Retrospective multicentre cohort study

Authors' conclusion

Routinely collected physiologic and patient data can be used to generate population-level cardiac index estimates in adult cardiac surgery patients when appropriately adjusted, though individual-level discrimination of low CI is limited.

Study context

Population
Adult cardiac surgical patients with thermodilution-based CI measurements, 7 US hospitals, 2014–2022
Participants
5,989 patients
Exposure
Formula-based CI estimates vs Thermodilution
Outcome
Accuracy of adjusted CI estimates vs thermodilution CI (Bland-Altman); concordance in classifying low CI (< 2.2 L/min/m²)
Methodological detailsseven US hospitals
  • Seven US hospitals

Main finding

As reported in the abstract

Accuracy of CI estimation
GroupValuepost-CPB median (IQR)Mean absolute error pre-bypassMean absolute error post-bypassCohen's kappa low CI pre-bypassCohen's kappa low CI post-bypass
Thermodilutionmedian 2.1 (IQR 1.8–2.6) L/min/m²2.4 (2.0-2.9)
Liljestrand and Zander0.450.470.260.20

Value

Thermodilutionmedian 2.1 (IQR 1.8–2.6) L/min/m²
Liljestrand and Zander— not stated in the abstract

post-CPB median (IQR)

Thermodilution2.4 (2.0-2.9)
Liljestrand and Zander— not stated in the abstract

Mean absolute error pre-bypass

Thermodilution— not stated in the abstract
Liljestrand and Zander0.45

Mean absolute error post-bypass

Thermodilution— not stated in the abstract
Liljestrand and Zander0.47

Cohen's kappa low CI pre-bypass

Thermodilution— not stated in the abstract
Liljestrand and Zander0.26

Cohen's kappa low CI post-bypass

Thermodilution— not stated in the abstract
Liljestrand and Zander0.20

Observational data: associations, not effects.

Original publication

Feasibility of estimating cardiac indices using cardiac surgery anesthesia records in a multicenter cohort. J Clin Monit Comput. Published 24 December 2025. doi:10.1007/s10877-025-01400-0

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