Cardiothoracic & vascular anesthesia
Feasibility of estimating cardiac indices using cardiac surgery anesthesia records in a multicenter cohort
Authors' conclusion
Routinely collected physiologic and patient data can be used to generate population-level cardiac index estimates in adult cardiac surgery patients when appropriately adjusted, though individual-level discrimination of low CI is limited.
Study context
- Population
- Adult cardiac surgical patients with thermodilution-based CI measurements, 7 US hospitals, 2014–2022
- Participants
- 5,989 patients
- Exposure
- Formula-based CI estimates vs Thermodilution
- Outcome
- Accuracy of adjusted CI estimates vs thermodilution CI (Bland-Altman); concordance in classifying low CI (< 2.2 L/min/m²)
Methodological detailsseven US hospitals
- Seven US hospitals
Main finding
As reported in the abstract
Accuracy of CI estimation
| Group | Value | post-CPB median (IQR) | Mean absolute error pre-bypass | Mean absolute error post-bypass | Cohen's kappa low CI pre-bypass | Cohen's kappa low CI post-bypass |
|---|---|---|---|---|---|---|
| Thermodilution | median 2.1 (IQR 1.8–2.6) L/min/m² | 2.4 (2.0-2.9) | ||||
| Liljestrand and Zander | 0.45 | 0.47 | 0.26 | 0.20 |
Value
Thermodilutionmedian 2.1 (IQR 1.8–2.6) L/min/m²
Liljestrand and Zander— not stated in the abstract
post-CPB median (IQR)
Thermodilution2.4 (2.0-2.9)
Liljestrand and Zander— not stated in the abstract
Mean absolute error pre-bypass
Thermodilution— not stated in the abstract
Liljestrand and Zander0.45
Mean absolute error post-bypass
Thermodilution— not stated in the abstract
Liljestrand and Zander0.47
Cohen's kappa low CI pre-bypass
Thermodilution— not stated in the abstract
Liljestrand and Zander0.26
Cohen's kappa low CI post-bypass
Thermodilution— not stated in the abstract
Liljestrand and Zander0.20
Observational data: associations, not effects.
Original publication
Feasibility of estimating cardiac indices using cardiac surgery anesthesia records in a multicenter cohort. J Clin Monit Comput. Published 24 December 2025. doi:10. 1007/ s10877-025-01400-0
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