Cardiothoracic & vascular anesthesia
Fibrinogen/Albumin Ratio and Outcome in Adult Cardiac Surgery With Cardiopulmonary Bypass
Authors' conclusion
The F/A ratio alone has poor predictive properties for major morbidity, and there is no added value in including the F/A ratio into the existing risk models.
Study context
- Population
- Adults undergoing cardiac surgery with cardiopulmonary bypass (CPB)
- Participants
- 836 adults
- Exposure
- EuroSCORE II-based model with vs without F/A ratio; F/A ratio alone
- Outcome
- Major morbidity (≥1 of: surgical revision for any cardiac reason; stroke; AKI requiring RRT; deep sternal wound infection; prolonged mechanical ventilation)
Main finding
As reported in the abstract
Prediction of major morbidity
| Group | AUC |
|---|---|
| F/A ratio alone | 0.606 |
| EuroSCORE II | 0.731 |
| EuroSCORE II + F/A ratio | 0.730 |
AUC
F/A ratio alone0.606
EuroSCORE II0.731
EuroSCORE II + F/A ratio0.730
- EuroSCORE II vs F/A ratio alone: P < 0.001 — significantly better AUC
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value |
|---|---|---|
| Univariate association of F/A ratio with major morbidityF/A ratio vs EuroSCORE II | 1.025 (1.061–1.091) | P = 0.004 |
Original publication
Fibrinogen/Albumin Ratio and Outcome in Adult Cardiac Surgery With Cardiopulmonary Bypass. Anesth Analg. Published 24 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →