Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes
Authors' conclusion
Long-term outcome in patients supported with ECMO is good. Five-year survivors reported that HRQoL was satisfactory despite some impairment in day-to-day functioning.
Study context
- Population
- Patients with respiratory or cardiac failure supported with extracorporeal membrane oxygenation (ECMO), ICUs of 10 ECMO centres in the Netherlands, August 2017–July 2019155 5-year survivors
- Participants
- 428 patients
- Exposure
- Respiratory support vs Cardiac support vs ECPR
- Outcome
- Survival and health-related quality of life (HRQoL)
- Follow-up
- 5 years
Methodological detailsmulticentre, observational, follow-up
- Multicentre
- Observational
- Follow-up
Main finding
As reported in the abstract
- Survived 5 years (all patients)
- 155 (36%)
- Survived hospital admission
- 230 (54%)
- Survived first year
- 213 (50%)
- EuroQol index at 5 years, median (IQR 0.73-0.98)
- 0.82
- Slight-to-moderate impairment of mobility
- 39%
- Impairment of usual activities
- 44%
- Pain or discomfort
- 60%
- Employed
- 41%
- Retired
- 31%
- Permanently declared unfit for work
- 26%
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes. Crit Care Med. Published 15 October 2025. doi:10.
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