Glucose measurements with accu check inform II versus hexokinase plasma method during surgery under general anesthesia, an observational cohort study
Main finding · Agreement, all paired measurementsResult — go to the resultMean difference 0.0 mmol/L CI −0.7 to 0.7Authors' conclusion
The agreement between glucose measurements using ACI II and the reference laboratory hexokinase test was clinically acceptable with a percentage error of 10.0% (95% CI 8.0 to 11.9).
Study context
- Population
- Patients undergoing surgery with GA (maintenance with Sevoflurane or Total intravenous anesthesia (TIVA)); glucose measured before and after induction78 measurements
- Participants
- 39 patients
- Exposure
- ACI II vs Hexokinase
- Outcome
- Agreement between ACI II and hexokinase glucose measurements (Bland-Altman; percentage error)
Methodological detailsmethod comparison, Bland-Altman analysis
- Method comparison
- Bland-Altman analysis
Main finding
Agreement, all paired measurements
Mean difference
0.0 mmol/L
CI −0.7 to 0.7
ACI II vs Hexokinase
mean difference 0.0 mmol/L (CI −0.7 to 0.7)
As reported in the abstract
- Percentage error (clinically acceptable agreement)
- 10.0% (95% CI 8.0 to 11.9)
Observational data: associations, not effects.
Further findings
ACI II–hexokinase difference per test, Sevoflurane vs TIVA (subgroup)
- Sevoflurane, mean ± SD difference (mmol/L)
- −0.2 ± 0.4
- TIVA, mean ± SD difference (mmol/L)
- 0.4 ± 0.3
- Sevoflurane vs TIVA
- P < 0.001
Change in ACI II–hexokinase difference from before to after induction, Sevoflurane vs TIVA (subgroup)
- Sevoflurane, mean ± SD change in difference (mmol/L)
- 0.4 ± 0.4
- TIVA, mean ± SD change in difference (mmol/L)
- −0.4 ± 0.3
- Sevoflurane vs TIVA
- P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Glucose measurements with accu check inform II versus hexokinase plasma method during surgery under general anesthesia, an observational cohort study. J Clin Monit Comput. Published 9 September 2023. doi:10.
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