Cardiothoracic & vascular anesthesia
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation: a randomised controlled trial
Authors' conclusion
This study has demonstrated that high flow, compared with standard oxygen therapy, does not improve arterial oxygenation over the course of the procedure.
Study context
- Population
- Patients undergoing transfemoral TAVI with conscious sedation
- Participants
- 72 patients
- Comparison
- HFNO vs standard oxygen therapy
- Primary endpoint
- Change in arterial pO2 during the procedure
Primary result
As reported in the abstract
Change in pO2 from baseline
High-flow
12.10 to 13.69
median · IQR [range] 10.05-15.22 [7.2-29.8] to 10.85-18.38 [8.5-32.3] · kPa
Standard oxygen therapy
15.45 to 14.20
median · IQR [range] 12.17-19.33 [9.2-22.8] to 11.80-19.40 [9.7-35.1] · kPa
Secondary outcomes
| Outcome | P value |
|---|---|
| Percentage change in pO2 · 30 minNot significantly different | P = 0.171 |
| Incidence of oxygen desaturationLower incidence in the high-flow group | P = 0.027 |
| Patient comfort scoreSignificantly higher in the high-flow group | P ≤ 0.001 |
Original publication
High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation: a randomised controlled trial. Perioper Med (Lond). Published 14 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →