Impact of a strategy based on unique blood culture sampling on contamination rate and detection of bloodstream infections in critically ill patients
Authors' conclusion
In ICU patients, a strategy based on UBC reduces the contamination rate of cultures without affecting their yield.
Study context
- Population
- Critically ill ICU patients undergoing blood culture sampling17,466 BC collected
- Participants
- 4,491 patients
- Comparison
- Unique blood culture strategy vs multi-sampling strategy
- Outcome
- Rate of BC contamination (BC contaminations (BCC)) and of bloodstream infection (bloodstream infections (BSI)) per patient
Methodological detailsmulti-faceted program, education and feedback, 4-month washout period with staff education and training between periods
- Multi-faceted program
- Education and feedback
- 4-month washout period with staff education and training between periods
Main finding
BC contamination per patient
Reduction
73.4%
P < 0.001
By group
As reported in the abstract
Further findings
BSI per patient
P = 0.98
Blood volume per bottle
P < 0.01
| Outcome | Reduction (95% CI) | P value |
|---|---|---|
| BC bottles collected per week | 59.6% (56.7–62.3) | P < 0.001 |
Original publication
Impact of a strategy based on unique blood culture sampling on contamination rate and detection of bloodstream infections in critically ill patients. Ann Intensive Care. Published 3 March 2023. doi:10. 1186/ s13613-023-01107-y
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