Sepsis & infection

Impact of a strategy based on unique blood culture sampling on contamination rate and detection of bloodstream infections in critically ill patients

Ann Intensive CarePublished Before-and-after study

Authors' conclusion

In ICU patients, a strategy based on UBC reduces the contamination rate of cultures without affecting their yield.

Study context

Population
Critically ill ICU patients undergoing blood culture sampling17,466 BC collected
Participants
4,491 patients
Comparison
Unique blood culture strategy vs multi-sampling strategy
Outcome
Rate of BC contamination (BC contaminations (BCC)) and of bloodstream infection (bloodstream infections (BSI)) per patient
Methodological detailsmulti-faceted program, education and feedback, 4-month washout period with staff education and training between periods
  • Multi-faceted program
  • Education and feedback
  • 4-month washout period with staff education and training between periods

Main finding

BC contamination per patient

Reduction

73.4%

P < 0.001

By group

As reported in the abstract

Further findings

BSI per patient

P = 0.98

Blood volume per bottle

P < 0.01

OutcomeReduction (95% CI)P value
BC bottles collected per week59.6% (56.7–62.3)P < 0.001

Original publication

Impact of a strategy based on unique blood culture sampling on contamination rate and detection of bloodstream infections in critically ill patients. Ann Intensive Care. Published 3 March 2023. doi:10.1186/s13613-023-01107-y

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