Cardiothoracic & vascular anesthesia
Impact of an Autotransfusion Device on Platelet Count and Transfusion Requirements in Cardiac Surgery: An Observational Study
Main finding · Platelet count decreaseResult — go to the resultMean difference 9.94 95% CI 1.99–18.58Authors' conclusion
Compared with ICS-centrifugation, ICS-filtration may offer advantages in platelet salvage for shed blood, thereby reducing transfusion requirements and related morbidity in cardiac surgery patients.
Study context
- Population
- Scheduled cardiac surgery patients with anticipated CPB ≥ 2 hours or aortic arch, redo or combined surgery, or multiple aorto-coronary bypasses; academic hospital, June 2021 to May 2024
- Participants
- 293 patients
- Exposure
- Intraoperative cell salvage (ICS)-centrifugation vs ICS-filtration
- ICS-centrifugationn = 208reference
- ICS-filtrationn = 85
- Outcome
- Decrease in platelet count between preoperative and postoperative assessments
Methodological detailsobservational, single-centre
- Observational
- Single-centre
Main finding
Platelet count decrease
Mean difference
9.94
95% CI 1.99–18.58
P = 0.02
By group
ICS-centrifugation vs ICS-filtration
mean difference 9.94 (95% CI 1.99–18.58); P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Intraoperative or postoperative transfusion · day 28
P = 0.03
Safety
| Outcome | ICS-centrifugation | ICS-filtration | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Overall postoperative morbidity · day 28 | 16.3% | 5.9% | 0.32 (0.11–0.78) | P = 0.03 | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Impact of an Autotransfusion Device on Platelet Count and Transfusion Requirements in Cardiac Surgery: An Observational Study. J Cardiothorac Vasc Anesth. Published 3 April 2026. doi:10.
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