Cardiothoracic & vascular anesthesia
Preservation of Platelet Function After Intraoperative Cell Salvage Using the i-SEP Same Device in Cardiac Surgery
Authors' conclusion
The Same device enabled recovery of functional platelets and red blood cells from cardiopulmonary bypass blood.
Study context
- Population
- Adults undergoing elective on-pump cardiac surgery (valve surgery, CABG), university tertiary care hospital31 analysed
- Participants
- 44 adults
- Exposure
- Reinfusion bag contents vs intraoperative patient blood
- Outcome
- Platelet function preservation after intraoperative autotransfusion (flow cytometry, impedance aggregometry)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Platelet count
P = 0.0072
- Relative platelet recovery, median (IQR 57.2-97.0%)
- 76.5%
- Estimated equivalent vs platelet concentrates, median (0.06-0.19 units); ≈11.4% of one platelet concentrate unit
- 0.11 units
- Platelet activation markers partially preserved: CD62P
- 40.4%
- CD63
- 52.5%
- PAC-1
- 82.8%
- Platelet aggregation partially retained: ASPI
- 34.0%
Observational data: associations, not effects.
Secondary outcomes
Hematocrit
P < 0.0001
Safety
- No adverse events occurred
Original publication
Preservation of Platelet Function After Intraoperative Cell Salvage Using the i-SEP Same Device in Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 22 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →