Cardiothoracic & vascular anesthesia
Incidence and Associations of Acute Kidney Injury After Lung Resection Surgery: A Systematic Review and Meta-analysis
Authors' conclusion
AKI is a common complication following thoracic lung resection surgery and is strongly associated with a broad spectrum of severe adverse postoperative outcomes.
Study context
- Population
- Patients undergoing thoracic lung resection surgery
- Participants
- 19,918 patients · 20 studies
- Comparison
- Acute kidney injury (AKI) vs no AKI after lung resection; GDFT vs control
- Outcome
- Incidence of AKI (RIFLE, Acute Kidney Injury Network (AKIN) or KDIGO criteria)
Methodological detailsprospectively registered protocol
- Prospectively registered protocol
Pooled result
As reported in the abstract
Pooled incidence of AKI
Pooled incidence of AKI
5.31%
95% CI 3.61%–6.70%
Mild AKI
5.51%
Moderate to severe AKI
0.96%
Further pooled results
Hospital stay, AKI vs no AKI
| Mean difference (days) (95% CI) | ||
|---|---|---|
| AKIProlonged hospital stay | 0.92 (0.52–1.30) | |
| −1012Difference, days (linear scale) |
Short-term mortality, AKI vs no AKI
| RR (95% CI) | ||
|---|---|---|
| AKIIncreased short-term mortality | 5.60 (1.66–18.83) | |
| 0.050.21520Relative risk (log scale) |
Risk of AKI with GDFT
| RR (95% CI) | ||
|---|---|---|
| GDFTDid not significantly reduce the risk of AKI | 0.64 (0.32–1.27) | |
| 0.20.5125Relative risk (log scale) |
Original publication
Incidence and Associations of Acute Kidney Injury After Lung Resection Surgery: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 25 April 2026. doi:10.
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