Cardiothoracic & vascular anesthesia
Incidence and Temporal Changes of Transfusion and Coagulation Management in Cardiac Surgery: Insights From the Netherlands Heart Registration
Authors' conclusion
Perioperative transfusion rates in Dutch cardiac surgery have increased and have substantial intercenter variability. The observed increase in RBC transfusions was not fully reflected by changes in measured patient and procedural characteristics.
Study context
- Population
- Adults undergoing cardiac surgery in all 16 Dutch cardiac surgery centres, Netherlands Heart Registration, 2016–2023
- Participants
- 110,366 adults · 16 centres
- Outcome
- Transfusion rates of RBCs, plasma, platelets, PCC, fibrinogen concentrate and recombinant factor VIIa
Methodological detailsnationwide, multicentre registry
- Nationwide
- Multicentre registry
Main finding
As reported in the abstract
Transfusion rates (patients with available data)
- Red blood cell (RBCs)
- 30.6%
- Plasma
- 11.0%
- Platelets
- 20.3%
- PCC
- 7.4%
- Fibrinogen concentrate
- 13.5%
- Recombinant factor VIIa
- 0.5%
Observational data: associations, not effects.
Secondary outcomes
Interhospital variability
- Significant variability between centres
Annual temporal trend in transfusion rates (OR per year)
- RBCs, OR
- 1.02 (95% CI 1.02-1.03)
- Plasma, OR
- 1.08 (95% CI 1.07-1.09)
- Platelets, OR
- 1.09 (95% CI 1.08-1.10)
- PCC, OR
- 1.10 (95% CI 1.09-1.11)
- Fibrinogen, OR
- 1.15 (95% CI 1.14-1.16)
Adjusted temporal trend in RBC transfusion per year (exploratory)
- aOR
- 1.03 (95% CI 1.02-1.04)
- Exploratory analyses
- Adjusted for patient and procedural characteristics
Original publication
Incidence and Temporal Changes of Transfusion and Coagulation Management in Cardiac Surgery: Insights From the Netherlands Heart Registration. J Cardiothorac Vasc Anesth. Published 4 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →