Cardiothoracic & vascular anesthesia
Incidence of Intraoperative Vasoplegic Syndrome in Lung Transplantation
Authors' conclusion
The incidence of VS in lung transplantation is comparable to that of cardiac surgery. Interestingly, male sex and cystic fibrosis are strong risk factors.
Study context
- Population
- Adults (≥18 years) undergoing single or bilateral lung transplantation, April 2013 to September 2021
- Outcome
- Incidence of vasoplegic syndrome (MAP <65 mmHg, cardiac index ≥2.2 L/min/m², ≥30 minutes of vasopressor after organ reperfusion)
Methodological detailssingle-centre, academic hospital
- Single-centre
- Academic hospital
Main finding
As reported in the abstract
Incidence of VS
Incidence of vasoplegic syndrome (VS)
13.9%
CI 10.4%–18.4%
Observational data: associations, not effects.
Further findings
Factors independently associated with VS (multivariate logistic regression)
| OR (CI) | P value | ||
|---|---|---|---|
| Male sexMultivariate model | 2.85 (1.07–7.58) | P = 0.04 | |
| Cystic fibrosisMultivariate model | 5.76 (1.43–23.09) | P = 0.01 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Incidence of Intraoperative Vasoplegic Syndrome in Lung Transplantation. J Cardiothorac Vasc Anesth. Published 20 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →