Respiratory failure & ventilation
Interventions Relieving Dyspnea in Intubated Patients Show Responsiveness of the Mechanical Ventilation–Respiratory Distress Observation Scale
Authors' conclusion
The MV-RDOS seems able to detect and monitor respiratory symptoms reasonably well in noncommunicative intubated patients.
Study context
- Population
- Communicative and noncommunicative mechanically ventilated patients with breathing difficulties25 noncommunicative
- Participants
- 50 participants
- Exposure
- Mechanical ventilation-respiratory distress observation scale (MV-RDOS) at baseline vs after ventilator adjustment vs after morphine
- Outcome
- MV-RDOS score, noncommunicative patients
Main finding
As reported in the abstract
Baseline
5.5
IQR 4.2–6.6
After ventilator adjustments
4.2
IQR 2.1–4.7
After morphine
2.5
IQR 2.1–4.2
After ventilator adjustments vs Baseline: P < 0.001 · After morphine vs Baseline: P = 0.024
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| MV-RDOS score in noncommunicative patientsAfter ventilator adjustments vs baseline | after morphine administration 2.5 (IQR 2.1–4.2) | P < 0.001 |
| MV-RDOS score in noncommunicative patientsAfter morphine administration vs baseline | P = 0.024 |
Relief of breathing difficulties
- Relief after ventilator adjustments
- 25 (50%)
- Relief in additional patients after morphine administration
- 21
Correlation of MV-RDOS with alae nasi/parasternal EMG activity
- MV-RDOS vs alae nasi EMG, positive correlation (ρ)
- 0.41
- MV-RDOS vs parasternal EMG, positive correlation (ρ)
- 0.37
MV-RDOS by EEG preinspiratory potentials
- MV-RDOS scores higher in patients with EEG preinspiratory potentials
- 4.9 [IQR, 4.2-6.3] vs. 4.0 [IQR, 2.1-4.9]; P = 0.002
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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