Hemodynamics, fluids & transfusion
Intra‐operative blood transfusion in elderly patients on antithrombotic therapy
Primary result · Intra-operative transfusion of packed RBCResult — go to the resultCrude odds ratio 1.51 95% CI 1.18–1.94Authors' conclusion
We found that chronic antithrombotic therapy was associated with intra-operative transfusion of packed red blood cells in elderly patients undergoing elective procedures in an unadjusted analysis, but not in a multivariate adjusted model.
Study context
- Population
- Patients aged ≥80 years undergoing elective procedures, 177 European centres, October 2017 to December 2018of 9497 POSE patients
- Participants
- 7,174 patients
- Comparison
- Chronic antithrombotic therapy vs no antithrombotic therapy
- Antithrombotic therapyn = 4,073
- Primary endpoint
- Intra-operative transfusion of packed RBCs
Methodological detailsmulticentre, multiple logistic regression
- Multicentre
- Multiple logistic regression
Primary result
Intra-operative transfusion of packed RBC
Crude odds ratio
1.51
95% CI 1.18–1.94
Events by treatment group
Antithrombotic therapy vs No antithrombotic therapy
crude OR 1.51 (95% CI 1.18–1.94)
As reported in the abstract
- Adjusted OR after multiple logistic regression (associated in unadjusted analysis, not in multivariate adjusted model)
- 0.98; 0.73-1.32
Original publication
Intra‐operative blood transfusion in elderly patients on antithrombotic therapy. Acta Anaesthesiol Scand. Published 13 February 2023. doi:10.
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