Cardiothoracic & vascular anesthesia
Intraoperative Factors Associated With Mechanical Ventilation Duration Following Aortic Surgery
Authors' conclusion
Transfusion volume and pre- to post-CPB changes in driving pressures and end-tidal carbon dioxide are significantly associated with postoperative ventilation duration. Intraoperative mechanical ventilator power is not a significant predictor of mechanical ventilation duration after major aortic surgery.
Study context
- Population
- Adults undergoing major aortic surgery requiring cardiopulmonary bypass (CPB) at a tertiary, high-volume cardiac surgery referral center
- Participants
- 647 adults
- Outcome
- Duration of postoperative ventilation (hours)
Methodological detailssingle-centre, mixed-effects regression
- Single-centre
- Mixed-effects regression
Main finding
As reported in the abstract
β
11.14 (95% CI [4.36, 17.91])
P < 0.001
Normalized transfusion volumes · mixed-effects regression
β
−2.29 (95% CI [−6.48, 1.90])
P = 0.52
Mechanical power · not associated
Patients included
9.0
median · IQR 6.0–14.4 · hours
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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