Cardiothoracic & vascular anesthesia
Intraoperative Hemolysis Monitoring by Real-time Point-of-care in Patients Undergoing Cardiopulmonary Bypass in Cardiac Surgery: A Single-centre Prospective Observational Study
Authors' conclusion
The use of Hemcheck Helge V-Test allows effective identification of hemolysis directly in the operating room, reducing wasted time for laboratory analyses.
Study context
- Population
- Patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB)
- Participants
- 78 patients
- Outcome
- Effectiveness of the point-of-care device Hemcheck Helge V-Test in quantifying hemolysis (plasma-free hemoglobin, PfHb, mg/dL) during cardiac surgery with CPB
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Median PfHb at intraoperative time points
- Hemolysis (plasma-free hemoglobin (PfHb) ≥50 mg/dL) at T0 (pre-CPB): no case
- 0
- Median PfHb (range) at T0 (pre-CPB), mg/dL
- 0.5 (0-7.1)
- Median PfHb (range) at T1 (aorta clamping), mg/dL
- 3.75 (0-14.4)
- Median PfHb (range) at T2 (20 minutes after CPB start), mg/dL
- 8.25 (0.4-19.1)
- Median PfHb (range) at T3 (end of CPB), mg/dL
- 27.5 (9.9-50)
- Median PfHb (range) at T4 (end of surgery), mg/dL
- 18.5 (2.4-41)
Observational data: associations, not effects.
Further findings
Association of hemolysis >50 mg/dL at T3 with CPB time >100 minutes · T3 (end of CPB)
- Statistically significant correlation between hemolysis >50 mg/dL at T3 and CPB time >100 minutes
- P < 0.05
Original publication
Intraoperative Hemolysis Monitoring by Real-time Point-of-care in Patients Undergoing Cardiopulmonary Bypass in Cardiac Surgery: A Single-centre Prospective Observational Study. J Cardiothorac Vasc Anesth. Published 28 February 2025. doi:10.
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