Cardiothoracic & vascular anesthesia
Intraoperative ketamine and pain after video-assisted thoracoscopic surgery (VATS): A systematic review and meta-analysis
Authors' conclusion
Intraoperative intravenous ketamine effectively reduces acute postoperative pain in VATS patients but does not significantly impact opioid consumption, hemodynamic parameters, and adverse events.
Study context
- Population
- Patients undergoing VATS
- Participants
- 1,151 patients · 10 randomized controlled trials (RCTs)
- Comparison
- Intraoperative IV ketamine vs normal saline
- Outcome
- Postoperative pain scores
Methodological detailsRisk of bias (RoB2) risk of bias assessment
- RoB2 risk of bias assessment
Pooled result
As reported in the abstract
Postoperative pain
MD
−0.65
P = 0.04
at 12 h
MD
−0.55 points
P < 0.01
at 48 h
Further pooled results
24-h postoperative opioid consumption, urine output, surgery duration, rescue analgesia, MAP, infusion volume, heart rate, extubation time, blood loss
- No significant difference
Original publication
Intraoperative ketamine and pain after video-assisted thoracoscopic surgery (VATS): A systematic review and meta-analysis. Anaesth Crit Care Pain Med. Published 16 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →