Cardiothoracic & vascular anesthesia
Intraoperative Versus Postoperative Hydroxocobalamin for Vasoplegic Shock in Cardiothoracic Surgery
Main findingResult — go to the resultEstimated difference 0.48 95% CI −1.76-2.72Authors' conclusion
A difference in vasopressor-free days after CPB was not found between patients who received hydroxocobalamin intraoperatively versus postoperatively for vasoplegic shock.
Study context
- Population
- Adults with vasoplegic shock undergoing cardiac surgery with cardiopulmonary bypass (CPB), quaternary academic cardiovascular surgery program
- Participants
- 112 adults
- Exposure
- Intraoperative vs postoperative hydroxocobalamin
- ORn = 37
- ICUn = 75reference
- Outcome
- Vasopressor-free days
- Follow-up
- First 14 days after CPB
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Estimated difference
0.48
95% CI −1.76-2.72
P = 0.67
OR vs ICU
estimated difference 0.48 (95% CI −1.76-2.72); P = 0.67
Observational data: associations, not effects.
Further findings
Postoperative renal failure, mesenteric ischemia, ICU and hospital LOS, in-hospital mortality
- Similar between groups
Original publication
Intraoperative Versus Postoperative Hydroxocobalamin for Vasoplegic Shock in Cardiothoracic Surgery. J Cardiothorac Vasc Anesth. Published 25 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →