Cardiothoracic & vascular anesthesia

Key Predictors of Early Extubation: A Modifiable Parameter Influencing Complications and Outcomes after Congenital Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Prospective cohort study

Authors' conclusion

Early extubation is a crucial modifiable parameter that has a significant influence on reduced complications, ICU stay, and hospital stay following congenital heart surgery.

Study context

Population
Patients undergoing cardiac surgery for congenital heart lesions by a single cardiac surgeon and anesthesiologist, 2023
Exposure
Extubation within 6 hours vs beyond 6 hours of surgery
Outcome
Reintubation, composite outcome, and length of ICU and hospital stay
Follow-up
30 days postoperatively
Methodological detailssingle-centre, fast-track extubation protocol, multivariate logistic regression
  • Single-centre
  • Fast-track extubation protocol
  • Multivariate logistic regression

Main finding

As reported in the abstract

Within 6 hours

65.49%

Within 6 hours vs Beyond 6 hoursOdds ratio (95% CI)P value
Composite outcomes; reported as lower odds
5.21(1.17–23.22)
P < 0.001
Prolonged ICU stay; reported as lower odds
12.73(2.72–59.66)
P < 0.001
Prolonged hospital stay; reported as lower odds
3.3(1.3–8.5)
P = 0.013
Reintubation; reported as lower odds
8.32 (95% CI 1.34–51.72); P = 0.02

Observational data: associations, not effects.

Further findings

Other predictors of outcomes

Age, RACHS-1 score, and durations of CPB, surgery, anesthesia and NIV also influenced outcomes

Original publication

Key Predictors of Early Extubation: A Modifiable Parameter Influencing Complications and Outcomes after Congenital Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 3 October 2025. doi:10.1053/j.jvca.2025.09.044

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