Respiratory failure & ventilation
Lower or higher oxygenation targets for acute Hypoxaemic respiratory failure: Protocol for an individual patient data meta‐analysis
Study context
- Population
- ICU patients with acute hypoxaemic respiratory failure, HOT-ICU and HOT-COVID trials2 RCTs
- Planned comparison
- Lower vs higher oxygenation target
- Primary endpoint
- All-cause mortality
- Follow-up
- 90 days
Methodological detailsone-step procedure, intention-to-treat, hierarchical general linear mixed model, 14 predefined subgroups, Secondary outcome: days alive without life-support at 90 days
- One-step procedure
- Intention-to-treat
- Hierarchical general linear mixed model
- 14 predefined subgroups
- Secondary outcome: days alive without life-support at 90 days
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Lower or higher oxygenation targets for acute Hypoxaemic respiratory failure: Protocol for an individual patient data meta‐analysis. Acta Anaesthesiol Scand. Published 7 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →