Respiratory failure & ventilation
Mechanical Power in Decelerating Flow versus Square Flow Ventilation in Pediatric Acute Respiratory Distress Syndrome
Authors' conclusion
Mechanical power was marginally lower in square flow than in decelerating flow, although the clinical significance of this is unclear.
Study context
- Population
- Children with ARDS (pediatric ARDS), ventilator metrics within 24 h of ARDS onset
- Participants
- 185 children
- Comparison
- Square flow vs decelerating flow ventilation
- Primary endpoint
- Mechanical power
- Follow-up
- Within 24 h of ARDS onset
Methodological detailspaired comparison, crossover of flow modes
- Paired comparison
- Crossover of flow modes
Primary result
As reported in the abstract
Mean difference
0.03 J · min-1 · kg-1
95% CI 0.014–0.038
P < 0.001
By group
Square flow vs Decelerating flow
mean difference 0.03 J · min-1 · kg-1 (95% CI 0.014–0.038); P < 0.001
Further findings
Mechanical power, age <2 yr and ≥2 yr (subgroups)
- Difference remained statistically significant in both age strata
Components of mechanical power in square flow
- Elastic contribution
- 70%
- Resistive contribution
- 30%
Original publication
Mechanical Power in Decelerating Flow versus Square Flow Ventilation in Pediatric Acute Respiratory Distress Syndrome. Anesthesiology. Published 27 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →