Hemodynamics, fluids & transfusion
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study
Main finding · In-hospital mortalityResult — go to the resultRisk difference 4.3% 95% CI 0.3%–8.3%Authors' conclusion
In patients admitted to ICU or HDU with AP receiving adequate fluid resuscitation, RS can be a preferred infusion treatment compared to NS.
Study context
- Population
- Adults hospitalized in intensive care units (ICU) or HDU for acute pancreatitis (AP) who survived at least 3 days and received sufficient fluid resuscitation within 3 days of admission; Japanese Diagnosis Procedure Combination database, July 2010–March 2021
- Participants
- 8,710 adults · 578 matched pairs
- Exposure
- Normal saline vs Ringer's solution
- Normal saline (NS)n = 657
- Ringer's solution (RS)n = 8,053reference
- Outcome
- In-hospital mortality
Methodological detailspropensity-score matched, nationwide inpatient database
- Propensity-score matched
- Nationwide inpatient database
Main finding
As reported in the abstract
Risk difference
4.3%
95% CI 0.3%–8.3%
Events by group
NS vs RS
risk difference 4.3% (95% CI 0.3%–8.3%)
Observational data: associations, not effects.
Original publication
Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study. J Intensive Care. Published 15 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →