Respiratory failure & ventilation
Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study
Main finding · Agreement of EXdi, standard ultrasound vs CUSdiResult — go to the resultAgreement bias 0.1 cm 95% CI −0.7-0.9Authors' conclusion
Operator-independent continuous diaphragm monitoring quantifies EXdi reliably and can predict weaning failure with an identified cut-off value of 1.1 cm.
Study context
- Population
- Mechanically ventilated patients during a 30-min spontaneous breathing trial (SBT)
- Participants
- 49 vs 36
- Exposure
- CUSdi vs Standard ultrasound
- CUSdin = 49
- Standard ultrasoundn = 36reference
- Outcome
- Agreement of EXdi, standard ultrasound vs CUSdi
Methodological detailsoperator-independent continuous ultrasound monitoring
- Operator-independent continuous ultrasound monitoring
Main finding
As reported in the abstract
Agreement bias
0.1 cm
95% CI −0.7-0.9
- Passing-Bablok regression: no systematic difference; positive correlation (Rho)
- 0.84
Observational data: associations, not effects.
Further findings
Weaning failure
- Weaning failure
- 54%
Prediction of weaning failure by EXdi < 1.1 cm · 2 min after SBT onset
- Sensitivity
- 0.83
- Specificity
- 0.68
- PPV
- 0.76
- NPV
- 0.24
EXdi, weaning success vs failure · 1, 2 and 3 min after SBT onset
- EXdi higher in weaning success than failure
Correlation of EXdi with Pdi parameters
- Peak Pdi, r
- 0.22 (95% CI 0.15 - 0.28)
- Pressure time product, r
- 0.13 (95% CI 0.06 - 0.20)
- Weak correlation
PCVdi
- Similar results to EXdi
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study. Crit Care. Published 16 July 2024. doi:10. 1186/ s13054-024-05003-0
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