Respiratory failure & ventilation

Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study

Crit CarePublished Prospective observational study

Main finding · Agreement of EXdi, standard ultrasound vs CUSdiResult — go to the resultAgreement bias 0.1 cm 95% CI −0.7-0.9

Authors' conclusion

Operator-independent continuous diaphragm monitoring quantifies EXdi reliably and can predict weaning failure with an identified cut-off value of 1.1 cm.

Study context

Population
Mechanically ventilated patients during a 30-min spontaneous breathing trial (SBT)
Participants
49 vs 36
Exposure
CUSdi vs Standard ultrasound
  • CUSdin = 49
  • Standard ultrasoundn = 36reference
Outcome
Agreement of EXdi, standard ultrasound vs CUSdi
Methodological detailsoperator-independent continuous ultrasound monitoring
  • Operator-independent continuous ultrasound monitoring

Main finding

As reported in the abstract

Agreement bias

0.1 cm

95% CI −0.7-0.9

Passing-Bablok regression: no systematic difference; positive correlation (Rho)
0.84

Observational data: associations, not effects.

Further findings

Weaning failure

Weaning failure
54%

Prediction of weaning failure by EXdi < 1.1 cm · 2 min after SBT onset

Sensitivity
0.83
Specificity
0.68
PPV
0.76
NPV
0.24

EXdi, weaning success vs failure · 1, 2 and 3 min after SBT onset

EXdi higher in weaning success than failure

Correlation of EXdi with Pdi parameters

Peak Pdi, r
0.22 (95% CI 0.15 - 0.28)
Pressure time product, r
0.13 (95% CI 0.06 - 0.20)
  • Weak correlation

PCVdi

Similar results to EXdi

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study. Crit Care. Published 16 July 2024. doi:10.1186/s13054-024-05003-0

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