Organ support & nutrition

Outcomes for patients with alcohol‐related liver disease admitted to Scottish intensive care units 2010–2018

AnaesthesiaPublished Retrospective cohort study

Main finding · ICU mortalityResult — go to the resultAdjusted odds ratio 2.03 95% CI 1.85–2.24

Authors' conclusion

Early mortality was high in patients with alcohol-related liver disease who were admitted to ICU, especially if multi-organ support was required.

Study context

Population
Adults admitted with emergency non-surgical diagnoses to general ICUs in Scotland, 2010–2018
Participants
49,420 emergency non-surgical ICU patients
Exposure
Alcohol-related liver disease vs No alcohol-related liver disease
  • Alcohol-related liver diseasen = 2,629
  • No alcohol-related liver diseasen = 46,791reference
Outcome
ICU mortality
Methodological detailssecondary data analysis, linked Scottish national databases, all adult general ICUs in Scotland
  • Secondary data analysis
  • Linked Scottish national databases
  • All adult general ICUs in Scotland

Main finding

As reported in the abstract

Adjusted odds ratio

2.03

95% CI 1.85–2.24

Events by group

Alcohol-related liver disease vs No alcohol-related liver disease
aOR 2.03 (95% CI 1.85–2.24)

Observational data: associations, not effects.

Secondary outcomes

Three-organ support

P < 0.001

Prevalence of alcohol-related liver disease among emergency non-surgical ICU admissions
5.3% · 2629
ICU mortality, alcohol-related liver disease presenting with gastrointestinal bleed (subgroup)
19.5% · 95
  • ICU mortality, alcohol-related liver disease presenting with gastrointestinal bleed (subgroup): 95/487

60-day mortality by organ support, alcohol-related liver disease (subgroup)

Zero organs supported
186/516 (36.0%)
Three organs supported
162/196 (82.7%)

Original publication

Outcomes for patients with alcohol‐related liver disease admitted to Scottish intensive care units 2010–2018. Anaesthesia. Published 11 March 2025. doi:10.1111/anae.16599

Composed by AI from the published abstract and checked against it. How Briefs are made →

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