Outcomes for patients with alcohol‐related liver disease admitted to Scottish intensive care units 2010–2018
Main finding · ICU mortalityResult — go to the resultAdjusted odds ratio 2.03 95% CI 1.85–2.24Authors' conclusion
Early mortality was high in patients with alcohol-related liver disease who were admitted to ICU, especially if multi-organ support was required.
Study context
- Population
- Adults admitted with emergency non-surgical diagnoses to general ICUs in Scotland, 2010–2018
- Participants
- 49,420 emergency non-surgical ICU patients
- Exposure
- Alcohol-related liver disease vs No alcohol-related liver disease
- Alcohol-related liver diseasen = 2,629
- No alcohol-related liver diseasen = 46,791reference
- Outcome
- ICU mortality
Methodological detailssecondary data analysis, linked Scottish national databases, all adult general ICUs in Scotland
- Secondary data analysis
- Linked Scottish national databases
- All adult general ICUs in Scotland
Main finding
As reported in the abstract
Adjusted odds ratio
2.03
95% CI 1.85–2.24
Events by group
Alcohol-related liver disease vs No alcohol-related liver disease
aOR 2.03 (95% CI 1.85–2.24)
Observational data: associations, not effects.
Secondary outcomes
Three-organ support
P < 0.001
- Prevalence of alcohol-related liver disease among emergency non-surgical ICU admissions
- 5.3% · 2629
- ICU mortality, alcohol-related liver disease presenting with gastrointestinal bleed (subgroup)
- 19.5% · 95
- ICU mortality, alcohol-related liver disease presenting with gastrointestinal bleed (subgroup): 95/487
60-day mortality by organ support, alcohol-related liver disease (subgroup)
- Zero organs supported
- 186/516 (36.0%)
- Three organs supported
- 162/196 (82.7%)
Original publication
Outcomes for patients with alcohol‐related liver disease admitted to Scottish intensive care units 2010–2018. Anaesthesia. Published 11 March 2025. doi:10. 1111/ anae. 16599
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