Regional anesthesia

Outpatient continuous adductor canal block (continuous adductor canal blocks (CACB)) for total knee arthroplasty: a double-blinded randomized placebo-controlled trial

Reg Anesth Pain MedPublished Randomised controlled trial

Authors' conclusion

In our study, CACB significantly enhanced early postoperative recovery and analgesia following TKA in an outpatient or short-stay setting, compared with SACB

Study context

Population
Patients undergoing primary total knee arthroplasty (TKA) in an outpatient or short-stay setting
Participants
60 patients
Comparison
Continuous vs single-injection adductor canal block
  • CACBn = 30
  • SACBn = 30reference
Primary endpoint
QoR-15 score
Follow-up
POD 2
Methodological detailsdouble-blind, placebo-controlled
  • Double-blind
  • Placebo-controlled

Primary result

As reported in the abstract

CACB

131.27

± 10.23

SACB

110.86

± 15.37

P < 0.001

Secondary outcomes

OutcomeCACBSACBP value
QoR-15 score · POD 1128.83 ± 12.36109.00 ± 15.90P < 0.001
QoR-15 score · POD 3131.97 ± 13.94111.18 ± 18.28P < 0.001

Opioid consumption and pain scores at rest and with movement · first three postoperative day (PODs)

Lower opioid consumption and pain scores with CACB

Safety

No major complications or signs of LAST observed

Original publication

Outpatient continuous adductor canal block (CACB) for total knee arthroplasty: a double-blinded randomized placebo-controlled trial. Reg Anesth Pain Med. Published 10 September 2025. doi:10.1136/rapm-2025-106991

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