Performance of the bispectral index and electroencephalograph derived parameters of anesthetic depth during emergence from xenon and sevoflurane anesthesia
Authors' conclusion
The BIS index is lower at equivalent stages of behavioural response during emergence from xenon anesthesia when compared to sevoflurane anesthesia, most likely due to differences in how these two agents influence the relative beta ratio.
Study context
- Population
- Participants scheduled for lithotripsy
- Participants
- 24 participants
- Comparison
- Xenon vs sevoflurane anaesthesia
- Primary endpoint
- Response of the BIS during emergence from xenon vs sevoflurane anesthesia
Primary result
As reported in the abstract
BIS index values at emergence timepoints · First response, eyes open, removal of airway
- BIS significantly lower with xenon than sevoflurane at each emergence timepoint
Further findings
Relative beta ratio · Emergence
- Increased significantly during emergence with sevoflurane but not with xenon
Spectral edge frequency and composite cortical state · Emergence
- Increased significantly in both groups during emergence
Original publication
Performance of the bispectral index and electroencephalograph derived parameters of anesthetic depth during emergence from xenon and sevoflurane anesthesia. J Clin Monit Comput. Published 19 April 2022. doi:10.
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