Haemodynamics, fluids & transfusion

Perioperative Anemia Development and Recovery in Adult Surgical Patients: An Observational Cohort Study

Anesth AnalgPublished observational cohort study

Authors' conclusion

Preoperative and postoperative anemia are highly prevalent, and anemia frequently persists for months after hospitalization. Older adults, women, and Black patients bear a disproportionate burden. Despite this, anemia evaluations and treatments remain underutilized. These findings highlight substantial opportunities for patient blood management (PBM) programs to improve perioperative anemia detection, optimization, and post-discharge management.

Study context

Population
Adults undergoing surgery at a large tertiary care medical center from August 2012 to July 2023patients undergoing 423,066 procedures (51.9% among women)
Participants
281,217 adults
Outcome
Preoperative anemia prevalence (World Health Organization (WHO) definitions), among those with available preoperative hemoglobin assessments (n = 308,959)
Follow-up
Preoperative

Main finding

As reported in the abstract

Overall, among those with available preoperative hemoglobin assessments
28.9%
Men
29.5%
Women
28.4%
Women, gender-neutral anemia definition
51.0%
Black patients
44.0%
Patients ≥75 years
39.6%
Spine surgery
18.6%
Vascular surgery
45.8%

Observational data: associations, not effects.

Further findings

New postoperative anemia among previously nonanemic patients admitted to the hospital postoperatively · postoperative hospitalization

Overall, among previously nonanemic patients admitted postoperatively
76.9%
Cardiac surgery (highest incidence)
97.5%
Women experienced more severe postoperative anemia than men

Anemia at hospital discharge

Patients anemic at hospital discharge
81.1%

Persistent anemia at 12 months

Among those discharged with mild anemia
28.5%
Among those discharged with moderate anemia
51.9%
Among those discharged with severe anemia
66.3%
Among patients nonanemic preoperatively who developed new postoperative anemia
29.3%
  • Recovery was gradual and incomplete

Original publication

Perioperative Anemia Development and Recovery in Adult Surgical Patients: An Observational Cohort Study. Anesth Analg. Published 6 October 2026. doi:10.1213/ane.0000000000008365

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