Cardiothoracic & vascular anesthesia

Perioperative cardiovascular pathophysiology in patients undergoing lung resection surgery: a narrative review

Br J AnaesthPublished Narrative review

Authors' conclusion

Aiding adaptation to the unique perioperative physiology seen in patients undergoing thoracic surgery could provide a novel therapeutic avenue to prevent cardiovascular complications and improve long-term functional capacity after surgery.

Study context

Population
Patients undergoing lung resection surgery

Main finding

As reported in the abstract

  • Good evidence of postoperative right ventricular dysfunction, persisting to at least 3 months
  • Dysfunction results from increased right ventricular afterload, intraoperatively and persisting postoperatively
  • Patients with reduced right ventricular contractile reserve and reduced pulmonary vascular flow reserve might struggle
  • Postoperative right ventricular dysfunction implicated in postoperative AF and perioperative myocardial injury
  • Under demands of critical illness or exercise, contractile and/or flow reserve can be overwhelmed: acute decompensation or impaired long-term functional capacity

Original publication

Perioperative cardiovascular pathophysiology in patients undergoing lung resection surgery: a narrative review. Br J Anaesth. Published 13 August 2022. doi:10.1016/j.bja.2022.06.035

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