Cardiothoracic & vascular anesthesia
Perioperative cardiovascular pathophysiology in patients undergoing lung resection surgery: a narrative review
Authors' conclusion
Aiding adaptation to the unique perioperative physiology seen in patients undergoing thoracic surgery could provide a novel therapeutic avenue to prevent cardiovascular complications and improve long-term functional capacity after surgery.
Study context
- Population
- Patients undergoing lung resection surgery
Main finding
As reported in the abstract
- Good evidence of postoperative right ventricular dysfunction, persisting to at least 3 months
- Dysfunction results from increased right ventricular afterload, intraoperatively and persisting postoperatively
- Patients with reduced right ventricular contractile reserve and reduced pulmonary vascular flow reserve might struggle
- Postoperative right ventricular dysfunction implicated in postoperative AF and perioperative myocardial injury
- Under demands of critical illness or exercise, contractile and/or flow reserve can be overwhelmed: acute decompensation or impaired long-term functional capacity
Original publication
Perioperative cardiovascular pathophysiology in patients undergoing lung resection surgery: a narrative review. Br J Anaesth. Published 13 August 2022. doi:10. 1016/ j. bja. 2022. 06. 035
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