Cardiothoracic & vascular anesthesia
Prebypass Critical Closing Pressure Predicts Acute Kidney Injury After Cardiopulmonary Bypass
Main finding · Prebypass PcritResult — go to the resultIncreased risk of AKI 16%Authors' conclusion
A higher prebypass Pcrit is associated with a significantly higher incidence of postoperative AKI.
Study context
- Population
- Adult cardiac surgery patients undergoing cardiopulmonary bypass (CPB) at a single tertiary care hospital
- Participants
- 1,038 patients
- Exposure
- Acute kidney injury (AKI) vs no AKI by prebypass critical closing pressure
- AKIn = 50
- Outcome
- AKI
Methodological detailssingle-centre
- Single-centre
Main finding
Prebypass Pcrit
Increased risk of AKI
16%
P = 0.011
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
- AKI incidence
- 5% · 50
Preoperative risk factors and operative times
- AKI patients had more severe CKD, higher STS risk score, longer operative and cross-clamp times
- P < 0.01
- All patients maintained at similar MAP on CPB
Original publication
Prebypass Critical Closing Pressure Predicts Acute Kidney Injury After Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. Published 12 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →