Cardiothoracic & vascular anesthesia
Predictive Factors of Mortality in Extracorporeal Membrane Oxygenation–Assisted Patients as a Bridge to Heart Transplantation
Authors' conclusion
In this study, the duration of ECMO did not emerge as a predictor of mortality; however, the need for hemodialysis and older age were associated with higher mortality in both the overall cohort and the transplanted patients. Donor BMI was identified as a significant predictor of mortality in both the short term and long term.
Study context
- Population
- Patients listed for urgent heart transplantation (HT) supported by extracorporeal membrane oxygenation (ECMO) as a bridge to HT, 2007–2024100 underwent HT (90.9%)
- Participants
- 110 patients
- Outcome
- In-hospital mortality (predictors)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
In-hospital mortality, overall cohort
In-hospital mortality rate, overall cohort (75 of 110 survived)
31.8%
Observational data: associations, not effects.
Further findings
In-hospital mortality, HT recipients (subgroup)
- In-hospital mortality rate among HT recipients (75 of 100 survived)
- 25%
- Predictors: age, need for hemodialysis, donor body mass index (BMI) < 10% (relative decrease in donor BMI < 10% vs recipient BMI), invasive mechanical ventilation at transplantation
Long-term mortality, HT recipients
- Independently predicted by age and donor BMI < 10%
Original publication
Predictive Factors of Mortality in Extracorporeal Membrane Oxygenation–Assisted Patients as a Bridge to Heart Transplantation. J Cardiothorac Vasc Anesth. Published 9 May 2025. doi:10.
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