Cardiothoracic & vascular anesthesia
Predictive Performances of Age, Creatinine, and Ejection Fraction (ACEF), ACEF II, Updated ACEF II, and European System for Cardiac Operative Risk Evaluation (EuroSCORE) II Risk Scores in Patients Undergoing Isolated Off-pump Coronary Artery Bypass Grafting
Authors' conclusion
ACEF I and II scores are reliable risk stratification models with performances comparable to the EuroSCORE II score in patients undergoing isolated OPCABG. However, the updated ACEF II score failed to demonstrate improved performance.
Study context
- Population
- Patients undergoing isolated off-pump CABG (off-pump coronary artery bypass grafting (OPCABG)) at a tertiary teaching center, 2013–2022
- Participants
- 936 patients
- Exposure
- ACEF I, ACEF II and updated ACEF II vs EuroSCORE II for predicting operative mortality
- Outcome
- Discrimination for operative mortality (C-statistic)
Methodological detailssingle-centre, external validation
- Single-centre
- External validation
Main finding
As reported in the abstract
| Group | AUC | 95% CI |
|---|---|---|
| ACEF I | 0.793 | 0.645-0.940 |
| ACEF II | 0.831 | 0.691-0.971 |
| Updated ACEF II | 0.698 | 0.524-0.872 |
| EuroSCORE II | 0.780 | 0.606-0.954 |
AUC
ACEF I0.793
ACEF II0.831
Updated ACEF II0.698
EuroSCORE II0.780
95% CI
ACEF I0.645-0.940
ACEF II0.691-0.971
Updated ACEF II0.524-0.872
EuroSCORE II0.606-0.954
- ACEF II vs updated ACEF II: P = 0.010 — significantly better discrimination for ACEF II
- ACEF II vs ACEF I: P = 0.118 — no significant difference
- ACEF II vs EuroSCORE II: 0.354 — no significant difference
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Predictive Performances of ACEF, ACEF II, Updated ACEF II, and EuroSCORE II Risk Scores in Patients Undergoing Isolated Off-pump Coronary Artery Bypass Grafting. J Cardiothorac Vasc Anesth. Published 14 August 2024. doi:10.
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