Cardiothoracic & vascular anesthesia

Predictors of Postoperative Morphine Milligram Equivalents in Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

CABG, liver disease, patient-controlled analgesia, younger age, and higher BMI are associated with increased narcotic use after cardiac surgery.

Study context

Population
Adults undergoing open cardiac surgery, excluding continuous IV narcotic drips and operative mortality456 females
Participants
1,604 adults
Outcome
Predictors of postoperative MME
Follow-up
POD 0 to 3
Methodological detailssingle-centre, academic medical center
  • Single-centre
  • Academic medical center

Main finding

As reported in the abstract

  • Morphine milligram equivalent (MME) 31.0% greater with coronary artery bypass grafting (CABG) (p < 0.001)
  • MME 76.3% greater with liver disease (p = 0.005)
  • MME 48.8% greater with PCA (p <0.001)
  • Younger age associated with increased MME (p < 0.001)
  • Higher body mass index (BMI) associated with increased MME (p < 0.001)

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Predictors of Postoperative Morphine Milligram Equivalents in Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 23 August 2024. doi:10.1053/j.jvca.2024.08.029

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