Prevalence and prognosis of hyperdynamic left ventricular systolic function in septic patients: a systematic review and meta-analysis
Pooled result · Prevalence of hyperdynamic LV systolic function; short-term mortalityResult — go to the resultOdds ratio 2.37 95% CI 1.47–3.80Authors' conclusion
The prevalence of hyperdynamic LV systolic function is not negligible in septic patients. Such a finding is associated with significantly higher short-term mortality as compared to normal LV systolic function.
Study context
- Population
- Adult septic patients4 studies
- Comparison
- Hyperdynamic vs normal left ventricular (LV) systolic function
- Outcome
- Prevalence of hyperdynamic LV systolic function and associated short-term mortality vs normal LV systolic function
Pooled result
As reported in the abstract
Prevalence of hyperdynamic LV systolic function; short-term mortality
Odds ratio
2.37
95% CI 1.47–3.80
P < 0.01
By group
Hyperdynamic
18.2%
pooled prevalence · 95% CI 12.5–25.8
Hyperdynamic vs Normal
OR 2.37 (95% CI 1.47–3.80); P < 0.01
Further pooled results
| Outcome | Mean difference (beats/min) (95% CI) | P value | |
|---|---|---|---|
| Heart rateI2 = 51% | 6.14 (3.59–8.69) | P < 0.0001 | |
| −50510Difference, beats/min (linear scale) |
| Outcome | Mean difference (cm) (95% CI) | P value |
|---|---|---|
| E/e' ratio | P = 0.43 | |
| LVEDDI2 = 73% | - 0.21 (- 0.33, - 0.09) | P < 0.001 |
E/e' ratio
- No difference in E/e' between normal and hyperdynamic LV systolic function
Original publication
Prevalence and prognosis of hyperdynamic left ventricular systolic function in septic patients: a systematic review and meta-analysis. Ann Intensive Care. Published 3 February 2024. doi:10.
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