Anesthetic drugs & techniques

Propofol-remifentanil patient-controlled sedation for endoscopic procedures: a prospective service audit

Can J AnaesthPublished Prospective service audit

Authors' conclusion

The results from our prospective service audit indicate that propofol-remifentanil patient-controlled sedation is a safe and reliable technique in patients undergoing endoscopic procedures.

Study context

Population
Patients referred for endoscopy after failure under endoscopist-administered sedation, refusal without general anesthesia (GA), or planned complex procedure, 2017–2021
Participants
670 procedures
Outcome
Adequacy of sedation (Modified Gloucester Scale) and patient satisfaction

Main finding

As reported in the abstract

Adequacy of sedation and patient satisfaction
All procedures accomplished with adequate sedation without need for ventilation or GA
670

Observational data: associations, not effects.

Safety

Adverse events (Tracking and Reporting Outcomes of Procedural Sedation)

Sentinel airway or respiratory events
0
Airway obstruction requiring simple airway maneuver
19/670 (2.8%)
Average body mass index (BMI) in patients with airway obstruction (documented in 18/19)
35 kg·m-2
Self-terminating apnea
7/670 (1%)
Vomiting
3/670 (0.4%)
Aspiration
0
Vasopressor required to maintain BP within 20% of preprocedure values
17/665 (2.6%)

Original publication

Propofol-remifentanil patient-controlled sedation for endoscopic procedures: a prospective service audit. Can J Anaesth. Published 9 October 2023. doi:10.1007/s12630-023-02593-1

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