Regional anesthesia

Proximal versus distal adductor canal catheters for total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials

Can J AnaesthPublished Systematic review and meta-analysis of randomised controlled trials

Pooled result · Cumulative opioid consumptionResult — go to the resultMD −4.86 95% CI −15.19 to 5.47

Authors' conclusion

These findings suggest that proximal vs distal adductor canal catheter placement in patients undergoing TKA may be equally effective for the outcomes of opioid consumption in the first 24 hr, pain scores at rest, and pain scores with movement in the first 24 hr.

Study context

Population
Adults undergoing total knee arthroplasty (TKA)
Participants
352 adults · 6 randomized controlled trials (RCTs)
Comparison
Proximal vs distal adductor canal catheters
  • Proximaln = 175
Outcome
Cumulative opioid consumption
Follow-up
First 24 hr
Methodological detailstrial sequential analysis, RoB-2 risk of bias appraisal
  • Trial sequential analysis
  • RoB-2 risk of bias appraisal

Pooled result

As reported in the abstract

MD

−4.86

95% CI −15.19 to 5.47

P = 0.36

Proximal vs Distal
MD −4.86 (95% CI −15.19 to 5.47); P = 0.36

Further pooled results

OutcomeMD (95% CI)P value
Pain scores with movement · first 24 hrFour RCTs; 246 patients−0.25 (−0.85 to 0.35)P = 0.42
OutcomeMD (95% CI)P value
Pain scores at restSix RCTs; 350 patients0.41 (−1.23 to 0.40)P = 0.32

Trial sequential analysis

Required information size not reached; Z-curve did not cross monitoring boundaries in any endpoint

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Proximal versus distal adductor canal catheters for total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials. Can J Anaesth. Published 11 October 2023. doi:10.1007/s12630-023-02552-w

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