Pseudomonas aeruginosa in Patients With Nosocomial Respiratory Infections: A Secondary Analysis of the European Network for ICU-Related Respiratory Infections
Authors' conclusion
P aeruginosa is a leading NRI pathogen, with prevalence varying across countries.
Study context
- Population
- ICU patients with nosocomial respiratory infection who underwent microbiological testing, 12 countries, May 2016–August 2019
- Participants
- 1,059 patients
- Primary endpoint
- Prevalence of P aeruginosa and associated risk factors
Methodological detailsmultinational (12 countries)
- Multinational (12 countries)
Primary result
As reported in the abstract
P aeruginosa prevalence
P aeruginosa detected in samples (n = 153)
14.5%
Antimicrobial resistance mechanisms (n = 55)
5.1%
Multidrug resistant, among these
19.6%
Carbapenemase-producing, among these
11.1%
Further findings
Pathogen identification
- Pathogens identified (710 of 1,059)
- 67%
- Primarily blood culture samples
- 78%
Diagnosis in P aeruginosa cases
- VAP
- 66%
Complications
- Septic shock and acute kidney injury (AKI) most frequent complications
Mortality
- No significant mortality differences with vs without P aeruginosa infection
Original publication
Pseudomonas aeruginosa in Patients With Nosocomial Respiratory Infections: A Secondary Analysis of the European Network for ICU-Related Respiratory Infections. Chest. Published 9 January 2026. doi:10. 1016/ j. chest. 2025. 12. 033
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