Sepsis & infection

Pseudomonas aeruginosa in Patients With Nosocomial Respiratory Infections: A Secondary Analysis of the European Network for ICU-Related Respiratory Infections

ChestPublished Secondary analysis of the European Network for ICU-Related Respiratory Infections prospective cohort study

Authors' conclusion

P aeruginosa is a leading NRI pathogen, with prevalence varying across countries.

Study context

Population
ICU patients with nosocomial respiratory infection who underwent microbiological testing, 12 countries, May 2016–August 2019
Participants
1,059 patients
Primary endpoint
Prevalence of P aeruginosa and associated risk factors
Methodological detailsmultinational (12 countries)
  • Multinational (12 countries)

Primary result

As reported in the abstract

P aeruginosa prevalence

P aeruginosa detected in samples (n = 153)

14.5%

Antimicrobial resistance mechanisms (n = 55)

5.1%

Multidrug resistant, among these

19.6%

Carbapenemase-producing, among these

11.1%

Further findings

Pathogen identification

Pathogens identified (710 of 1,059)
67%
Primarily blood culture samples
78%

Diagnosis in P aeruginosa cases

VAP
66%

Complications

Septic shock and acute kidney injury (AKI) most frequent complications

Mortality

No significant mortality differences with vs without P aeruginosa infection

Original publication

Pseudomonas aeruginosa in Patients With Nosocomial Respiratory Infections: A Secondary Analysis of the European Network for ICU-Related Respiratory Infections. Chest. Published 9 January 2026. doi:10.1016/j.chest.2025.12.033

Composed by AI from the published abstract and checked against it. How Briefs are made →

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