Cardiothoracic & vascular anesthesia
Quality comparison of autotransfusion devices in cardiac surgery: a prospective observational cohort study
Authors' conclusion
Wash quality and processing speed differed between autotransfusion devices and processing sets.
Study context
- Population
- Adults undergoing cardiac surgery with autologous cell salvage15 excluded, incomplete data
- Participants
- 130 adults
- Exposure
- Four autotransfusion devices and their processing sets
- Outcome
- Wash quality (removal ratios of heparin, potassium, PfHb, white blood cells (WBCs), platelets; reinfusion heparin and potassium concentrations) and processing speed (RBC recovery rate)
Methodological detailsquality improvement initiative, consecutive patients, Device settings per manufacturer recommendations for optimal wash quality
- Quality improvement initiative
- Consecutive patients
- Device settings per manufacturer recommendations for optimal wash quality
Main finding
As reported in the abstract
Wash quality and processing speed
- Heparin removal, all devices
- > 99%
- Potassium removal, all devices
- > 95%
- Platelet removal, all devices
- > 94%
- Plasma free hemoglobin (PfHb) removal, all devices
- > 85%
- Median [IQR] WBC removal ratio across processing sets (significant differences)
- 26 [19-33]% to 59 [42-68]%
- Median [IQR] heparin reinfusion concentration across processing sets (significant differences), U·mL-1 processed red cells
- 0.09 [0.08-0.11] to 0.63 [0.55-0.70]
- Median [IQR] red blood cell (RBC) recovery rate across processing sets (significant differences), mL RBC·min-1
- 8 [8-10] to 24 [22-25]
Observational data: associations, not effects.
Original publication
Quality comparison of autotransfusion devices in cardiac surgery: a prospective observational cohort study. Can J Anaesth. Published 4 February 2025. doi:10.
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