Quantitative relationship between anteriorization of alpha oscillations and level of general anesthesia
Authors' conclusion
Anteriorization, quantified by the difference between frontal and occipital alpha powers, continuously developed in conjunction with general anesthesia.
Study context
- Population
- Patients undergoing surgery under GA, EEG and BIS recorded from before induction until arousal36 analysed
- Participants
- 50 patients
- Outcome
- Correlation of frontal alpha power, occipital alpha power and their difference (anteriorization) with BIS value
Methodological details21-electrode EEG, locally weighted regression
- 21-electrode EEG
- Locally weighted regression
Main finding
As reported in the abstract
Spearman correlation (mean of Fisher transformations) with BIS value
Frontal alpha power vs BIS, 95% CI
- 0.68, - 0.26
Occipital alpha power vs BIS, 95% CI
0.02, 0.62
Frontal–occipital alpha power difference vs BIS, 95% CI
- 1.11, - 0.91
Observational data: associations, not effects.
Further findings
Change in alpha powers with BIS value by anesthetic agent
- Frontal and occipital alpha power changes differed by anesthetic agent; the frontal–occipital difference was more consistent, with smaller individual variance
Original publication
Quantitative relationship between anteriorization of alpha oscillations and level of general anesthesia. J Clin Monit Comput. Published 1 November 2022. doi:10.
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