Hemodynamics, fluids & transfusion
Red Blood Cell Transfusion Requirements Before and After Implementation of a Perioperative Patient Blood Management Program in Adult Patients Undergoing Cardiac Surgery. A Before and After Observational Study
Main findingResult — go to the resultOdds ratio 0.55 95% CI 0.36–0.85Authors' conclusion
A perioperative PBM program in adult patients undergoing cardiac surgery was associated with a significant reduction in perioperative RBC transfusion, which persisted at day 30.
Study context
- Population
- Adults scheduled for cardiac surgery, single-centre French university teaching hospital, January 2021 to July 2022
- Participants
- 434 adults
- Exposure
- Post-PBM vs pre-PBM period
- post-PBMn = 221
- pre-PBMn = 213reference
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Odds ratio
0.55
95% CI 0.36–0.85
P = 0.007
Events by group
post-PBM vs pre-PBM
OR 0.55 (95% CI 0.36–0.85); P = 0.007
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Median number of RBC units transfused within transfused patients | P = 0.025 |
| RBC transfusion effects · day 30 after surgery | P = 0.029 |
Median number of red blood cell (RBC) units transfused within transfused patients
- Patient blood management (PBM) program associated with a reduction
RBC transfusion effects · day 30 after surgery
- Effects persisted at day 30
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Red Blood Cell Transfusion Requirements Before and After Implementation of a Perioperative Patient Blood Management Program in Adult Patients Undergoing Cardiac Surgery. A Before and After Observational Study. J Cardiothorac Vasc Anesth. Published 20 October 2023. doi:10.
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